Express Scripts FoundationServices
Personalized Medicine
A More Precise Approach to Choosing Treatments and Doses
No two people respond exactly the same way to a given drug. If prescribers could predict which patients are likely to respond to certain drugs and at what dose, patient outcomes may improve. Thanks to programs based on advances in pharmacogenomics, you and other clinicians now have that opportunity.
Where Do Pharmacogenomic Tests Fit In?
A pharmacogenomic test can identify variations in a patient's genes that affect the efficacy and safety of drug therapy. New tests let you consider relevant genetic variants — often related to the rate at which an individual metabolizes a given drug — and thus make better-informed prescribing decisions. This personalized approach to prescribing:
- Reduces waste because patients get the right drug and the right dose faster
- Enables more precise therapy and dosing decisions
- Increases the probability of successful therapy
- Lowers the risk of adverse effects
Advantages in Care and Value
Express Scripts programs facilitate pharmacogenomic testing and provide information that helps you make personalized prescribing decisions — selecting the right drug and the right dose more quickly, safely and effectively. Focusing on this mission, our pharmacogenomic programs can improve care and help lower overall healthcare costs.
We identify patients who may benefit from testing, engage you and the patient in a therapeutic alliance, and coordinate genetic testing, laboratory analysis, and feedback on testing results.
Our specialist pharmacists and genetic counselors have advanced training and unparalleled experience and are available to help you interpret test results and consider therapy changes.
Current Testing Programs
- BCR-ABL testing for Gleevec, Sprycel and Tasigna
- CCR5 tropism testing for Maraviroc
- CYP2C9 & VKORC1 testing for Warfarin
- CYP2C19 testing for Clopidogrel
- HLA-B*5701 testing for Abacavir
