Innovating For Better: 30+ Years and Counting
From the beginning, our members have been our focus. On their behalf, we’ve acted first to tackle the toughest challenges in health care, even when we acted alone. And we’re just getting started.
Read MorePhysician Innovation
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Express Scripts Data Shows Value-Based Programs Deliver Better Health, Affordability for Costly Conditions
Read More5 Reasons to Switch to Home Delivery
Home delivery is safe, convenient, and makes maintenance medications more affordable for Americans.
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Express Scripts Offers New Value-Based Program for Migraine
Industry first SafeGuardRx Migraine Care Value Program Brings Affordability to Migraine Prevention and Treatment for Patients and Payers
Read MoreExpress Scripts Flattens the Trajectory of the Diabetes Epidemic with SafeGuardRx Diabetes Care Value® Program
In its first year, the Express Scripts Diabetes Care Value program delivered nearly $43 million savings for plans; reduced heart attack risk in 15 percent of patients
Read MoreTaking on Your Toughest Challenges
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SafeGuardRx Improves Affordability and Access to Budget-Busting Drugs
By addressing the unsustainable cost trajectory facing employers and health plans, SafeGuardRxSM is transforming the pharmacy benefit.
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Financial Assistance Programs Positively Impact Adherence
Patients with inflammatory conditions and multiple sclerosis can overcome barriers to taking their medications with the help of financial assistance programs.
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PCSK9 Therapy: An Example of Value-Based Care
Working with Regeneron and Sanofi, Express Scripts directly delivers drug-specific savings to patients, making PCSK9 therapy more affordable and more accessible.
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SafeGuardRx: Better Care at a Lower Cost for Patients and Payers
New data shows significantly improved clinical outcomes and lower drug spending for patients with complex, high-cost conditions enrolled in our SafeGuardRxSM programs.
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Ask The Pharmacist: How Can I Make the Most of My Pharmacy Benefit?
Express Scripts Pharmacist Paul Reyes provides tips for understanding your benefit and getting more value out of it.
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Improving Health Care With Physician Connectivity
Technology helps physicians quickly and easily make the best clinical and most affordable prescribing decisions for their patients.
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Nonadherence Puts Patients With Multiple Sclerosis on a Dangerous Path
Patients diagnosed with multiple sclerosis (MS) face unpredictable and increasingly debilitating symptoms. Nonadherence can make these adverse events more costly and dangerous.
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SafeGuardRx: Delivering Better Health and Affordability
This first-to-market value-based program improves patient engagement and increases medication adherence while reducing costs for some of the costliest therapies.
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Helping Physicians by Creating a Simpler Pharmacy Experience
Industry leading, data-driven tools and programs help prescribers make the best therapy decisions for patients at the point-of-care.
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Reducing Diabetes Drug Spending and Health Risk
The Express Scripts Diabetes Care Value program reduced diabetes drug spending by 19% and reduced heart attack risk in 15% of patients.
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Digital Solutions Are Just One Way to Help Ease Physicians' Burden
More than half of physicians report having less free time than when they first started practicing. We're creating a simpler pharmacy experience to reduce administrative burden.
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$25 Million Targeting Early-Stage Health Care Innovation
Our multi-year commitment to Lewis & Clark Ventures specifically targets new techologies and companies with the potential to provide early acces to the next big ideas in health care.
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Accredo is Committed to Caring for Those Living With a Rare Disease
Accredo's holistic rare disease patient care yields a 27% increase in medication adherence.
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Members in Consumer Directed Health Plans Need Tools to Make Informed Decisions
Express Scripts takes a holistic approach to supporting members enrolled in Consumer Directed Health Plans.
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Health Connect 360: Better Health Outcomes – Guaranteed
Express Scripts offers the industry's first outcomes-based model of care that guarantees clinical targets and connects patient touchpoints across the care continuum.
Read MoreAmazon's Alexa Helps Members Check Their Prescription Order Status And More
Our innovative approach to health care offers new opportunities to deliver better outcomes for our members.
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Lowering Costs
Lowering costs while providing high-quality care shouldn’t require compromises.

Improving Health
The challenges you face in improving the health of your members may seem daunting.
