Innovating For Better: 30+ Years and Counting
From the beginning, our members have been our focus. On their behalf, we’ve acted first to tackle the toughest challenges in health care, even when we acted alone. And we’re just getting started.
Read MoreExpress Scripts Data Shows Value-Based Programs Deliver Better Health, Affordability for Costly Conditions
Read MoreExpress Scripts Offers New Value-Based Program for Migraine
Industry first SafeGuardRx Migraine Care Value Program Brings Affordability to Migraine Prevention and Treatment for Patients and Payers
Read MoreExpress Scripts Flattens the Trajectory of the Diabetes Epidemic with SafeGuardRx Diabetes Care Value® Program
In its first year, the Express Scripts Diabetes Care Value program delivered nearly $43 million savings for plans; reduced heart attack risk in 15 percent of patients
Read MoreManaging the Complexities of Federal and Public Sector Plans
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Proudly Serving America’s Labor Unions
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SafeGuardRx Improves Affordability and Access to Budget-Busting Drugs
By addressing the unsustainable cost trajectory facing employers and health plans, SafeGuardRxSM is transforming the pharmacy benefit.
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PCSK9 Therapy: An Example of Value-Based Care
Working with Regeneron and Sanofi, Express Scripts directly delivers drug-specific savings to patients, making PCSK9 therapy more affordable and more accessible.
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3 Trends Changing Health Care in 2018
Innovative treatments, new technologies and greater connectivity bring promise to the health care landscape.
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SafeGuardRx: Better Care at a Lower Cost for Patients and Payers
New data shows significantly improved clinical outcomes and lower drug spending for patients with complex, high-cost conditions enrolled in our SafeGuardRxSM programs.
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Nonadherence Puts Patients With Multiple Sclerosis on a Dangerous Path
Patients diagnosed with multiple sclerosis (MS) face unpredictable and increasingly debilitating symptoms. Nonadherence can make these adverse events more costly and dangerous.
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SafeGuardRx: Delivering Better Health and Affordability
This first-to-market value-based program improves patient engagement and increases medication adherence while reducing costs for some of the costliest therapies.
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Reducing Diabetes Drug Spending and Health Risk
The Express Scripts Diabetes Care Value program reduced diabetes drug spending by 19% and reduced heart attack risk in 15% of patients.
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Getting to the Rare Diagnosis: 7.6 Years and 7 Different Doctors
For patients with rare disease, getting to the right diagnosis is just the beginning of their journey. Our Rare Conditions Care Value Program® offers personalized support to help patients manage their...
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SafeGuardRx Enhancements: Further Optimizing Care and Value
Expanded discounts, pharmacogenomic testing and innovative patient engagement tools offered by three SafeGuardRx® programs.
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A Call for A Consensus: Price Increases in Branded Drugs Are Unsustainable
Since 2008, brand medications have risen in price an average 232%. We need to work with pharma and the government for common-sense legislation and regulatory changes.
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Lowering Costs
Lowering costs while providing high-quality care shouldn’t require compromises.

Improving Health
The challenges you face in improving the health of your members may seem daunting.


Managing Complex & Chronic Disease
Health care remains uncoordinated and costly. Consider diabetes, one of the most expensive conditions to manage. Prevalence continues to rise, despite advancements.

INFOGRAPHIC: Diabetes – The Most Costly Therapy Class Demands Attention
Express Scripts is working to control costs with high-touch clinical care for the more than 30 million people in the U.S. living with diabetes.
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Improving Care for Patients Living With Asthma, COPD and Multiple Sclerosis
Two new SafeGuardRx® programs unite our personalized care model with new strategies developed and tested in the Express Scripts Lab.
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A Wholehearted Solution: Cardiovascular Care ValueSM
Express Scripts’ new Cardiovascular Care ValueSM program expands on our SafeGuardRx® Cholesterol Care ValueSM program to holistically tackle the clinical and financial...
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Moving forward and doing more, together
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Express Scripts Leads Industry with New HIV Prevention Program
The HIV Care ValueSM program, part of the company’s SafeGuardRx® platform, will drive value and improve cost predictability for employers, health plans, and people at risk for HIV.
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