Ezetimibe

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Ezetimibe

Brand Zetia

 

Form Oral Tablet
Drug Type Cholesterol absorption inhibitors 
ezetimibe-drug-image

Ezetimibe is used to treat high cholesterol.

 

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Drug Information

Ezetimibe is used to treat high cholesterol.

Ezetimibe is sometimes given together with other cholesterol-lowering medications.

Ezetimibe may also be used for purposes not listed in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Ezetimibe is usually taken once daily at the same time each day.

You may take ezetimibe with or without food.

Ezetimibe may be taken at the same time with fenofibrate, or with a statin medication such as atorvastatin, lovastatin, simvastatin, pravastatin, or fluvastatin.

Your treatment may also include diet, exercise, weight control, and blood tests.

You may need frequent medical tests, even if you have no symptoms.

Your cholesterol levels may not improve for up to 2 weeks.

Store at room temperature away from moisture and heat.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Ezetimibe can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

Side effects may be more likely in older adults.

Common side effects may include:

  • diarrhea;
  • cold symptoms such as stuffy nose, sneezing, sore throat;
  • pain in an arm or leg;
  • joint pain; or
  • muscle pain while taking ezetimibe with a statin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Avoid eating foods high in fat or cholesterol, or ezetimibe will not be as effective.

If you also take other cholesterol medication: Take ezetimibe 2 hours before or 4 hours after taking cholestyramine, colestipol, or colesevelam.

Tell your doctor about all your other medicines, especially:

  • cyclosporine;
  • fenofibric acid;
  • gemfibrozil; or
  • a blood thinner --warfarin, Coumadin, Jantoven.

This list is not complete. Other drugs may affect ezetimibe, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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